Calcium/CaMK IV & Inflammatory Bowel Disease/Ruptured AAA: Protocol & Exploration of Prehospital Care

“Calcium/Calmodulin-Dependent Protein Kinase (CaMK) IV and Inflammatory Bowel Disease”

Presenter: Sidrah Khan (Advisor: Dr. Kevin Mollen) 

Inflammatory bowel disease is currently perceived as a chronic, relapsing idiopathic inflammatory condition of the gastrointestinal tract with a multfactorial pathogenesis. Our lab is beginning to elucidate the role the epithelial cell, rather than immune cell, plays in initiating and propagating this spectrum of diseases.

“Ruptured AAA: Protocol and Exploration of Prehospital Care”

Presenter: Amanda Phillips (Advisor: Dr. Edith Tzeng)

Ruptured abdominal aortic aneurysms (AAA) are still associated with exceedingly high overall mortality (~90%), despite advances in care. For those who survive to hospitalization, death still occurs in 20-40%. Decision making in the context of AAA is complex, and data have emerged that regional and institutional protocols that minimize variation in care markedly improve survival. Our lab is creating a protocol specific to the management of AAA in our healthcare system.

Journal Club paper: Upregulation of PD-1 follows tumour development in the AOM/DSS model of inflammation-induced colorectal cancer in mice. Immunology. 2019 Sep;158(1):35-46.