Date
November 5, 2020 - 8:30amEvent Description
Presenter: Stephen Badylak, DVM, PhD, MD
The extracellular matrix of healthy tissue represents the ideal microenvironment for cell, tissue and organ homeostasis. A variety of therapeutic “biologics” have become available in the past 20 years for use in topical wound care, dura mater replacement, cardiac patches, fistula plugs, and soft tissue repair/reconstruction, especially ventral hernia repair (among others). The mechanical and material property of surgical meshes for soft tissue repair is of obvious importance to surgeons, but resistance to infection, degradation rate, handling characteristics and cost affect the choice of the most appropriate surgical mesh for each patient and each pathology. The Badylak laboratory has investigated and identified properties of such ECM-based materials that influence the host/patient response and will be the focus of discussion in this seminar.
Recent articles on this topic from Dr. Badylak:
- Extracellular Matrix-Based Biomaterials and Their Influence Upon Cell Behavior. Cramer MC, et al. Ann Biomed Eng. 2020. PMID: 31741227
- Matrix-bound nanovesicles within ECM bioscaffolds. Huleihel L, et al. Sci Adv. 2016. PMID: 27386584 Free PMC article.
Location and Address
Zoom virtual meeting
Zoom meeting logon info has been emailed to Department of Surgery staff. For Pitt and UPMC staff outside the department who wish to access the lecture, please email surgerywebmaster@upmc.edu.