Heme Metabolism and Host Defense: Cross Signals During Macrophage Activation
Presenter: Dr. Janet Lee
Simmons Research Conferences
Tertiary Lymphoid Organs in Transplantation
Presenter: Dr. Martin Oberbarnscheidt
Dr. Oberbarnscheidt's lab investigates mechanisms behind formation of tertiary lymphoid organs (TLO) post transplantation. TLO form at local sites of chronic immune activation and have been associated with poor prognosis in autoimmune diseases and improved prognosis in cancer. Their formation and function in transplantation is not clearly understood, but they have been associated with chronic rejection.
The Effect of Neutrophil Extracellular Traps in Awakening Dormant Cancer Cells in the Tumor Microenvironment
Presenter: Dr. Christof Kaltenmeier (advisor: Drs. Samer Tohme / Michele Molinari)
cGAS is Critical in Maintaining the Crosstalk Between Cell Death and Autophagy During Intestinal Inflammation
Presenter: Dr. Sidrah Khan (advisor: Dr. Kevin Mollen)
Vascular Pulsatility: Effect of Mechanics on Gene Expression / Changes in Multiorgan Heart Transplants Following the 2018 Allocation Policy Change
Presenter: Dr. Derek Afflu (advisor: Dr. Edith Tzeng)
Alternative Conduits Have Worse Outcomes than Prosthetic Grafts In Infra-inguinal Bypass / Investigating the Role of Metformin in Improving Immune Defects Associated with Aging
Alternative Conduits Have Worse Outcomes than Prosthetic Grafts In Infra-inguinal Bypass
Presenter: Dr. Othman Abdul Malak (advisor: Dr. Edith Tzeng)
FATal Signaling by Oxidized Phospholipids: Implications for Drug Discovery in Acute Brain Injury
Presenter: Dr. Hülya Bayir
A Computational Analysis of Dynamic, Multi-Organ Inflammation induced by Endotoxin in Mice
Presenter: Dr. Ruben Zamora
Dr. Zamora is a Research Professor of Surgery at the University of Pittsburgh, and a long-term collaborator of Dr. Vodovotz. Their research team employs computational and systems biology approaches to inflammation in multiple disease states (sepsis/trauma, wound healing, chronic inflammatory diseases, and cancer), coupled to biochemical, cellular, animal, and clinical studies, with the goal of rational inflammation reprogramming.
Recent relevant publications
The MetfOrmin Benefits Lower Extremities with Intermittent Claudication (MOBILE IC) Trial / Designing a Novel Small Vessel Vascular Graft to Improve Patency
"The MetfOrmin Benefits Lower Extremities with Intermittent Claudication (MOBILE IC) Trial"
Presenter: Katherine Reitz (advisors: Drs. Matthew Neal, Edith Tzeng, Brian Zuckerbraun, and Daniel Hall)