Department of Surgery

Simmons Research Conferences

"Purinergic Receptor P2Y6 Mediated Arteriogenesis" and "Inflammasome-Mediated Effects of SARS-related proteins on Muscle Satellite Cells in Peripheral Arterial Disease"

"Purinergic Receptor P2Y6 Mediated Arteriogenesis"

Presenter: Rohan Kulkarni, MD (mentor: Ryan McEnaney, MD)

Dr. Kulkarni will discuss how purine nucleotides released into circulation influence the growth and maturation of collateral blood vessels when binding to P2Y receptor 6.


"Inflammasome-Mediated Effects of SARS-related proteins on Muscle Satellite Cells in Peripheral Arterial Disease"

Presenter: Bowen Xie, MD (mentor: Ulka Sachdev, MD)

Past, Present, and Future of Designing a Novel Small Caliber Synthetic Vascular Graft - Transitioning from Bench to Animal

Presenter: JB Moses, MD

Peripheral artery disease is a growing problem with significant economic impact. Current synthetic bypass grafts offer poor long-term patency for distal small vessel disease defined as less than 6mm in diameter.  From idea to prototype, Dr. Moses will be discussing his group's most recent prototypes and the shift from bench to animal models.  He will again briefly discuss a more recent project aimed at evaluating best medical management versus surgical management for patients with claudication.